Overview

NCI Definition: A primary, usually low grade adenocarcinoma of the endometrium in which the majority of the malignant epithelial cells contain abundant intracytoplasmic mucin. [1]

Endometrial mucinous adenocarcinomas most frequently harbor alterations in TP53, PTEN, PIK3CA, and KRAS [2].

TP53 c.217-c.1178 Missense, TP53 Mutation, TP53 Missense, TP53 P190L, and TP53 Exon 7 Mutation are the most common alterations in endometrial mucinous adenocarcinoma [2].

Disease Details

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.