Overview

NCI Definition: An uncommon mature T-cell lymphoma of intraepithelial lymphocytes. It usually arises from the small intestine, most commonly the jejunum or ileum. Other less frequent primary anatomic sites include the duodenum, stomach, colon, or outside the gastrointestinal tract. It is seen with increased frequency in regions with a high prevalence of celiac disease. [1]

Significant Genes in Enteropathy-Associated T-Cell Lymphoma

ALK +

BIRC2 +

BIRC3 +

CARD11 +

CD79A +

CD79B +

NFKBIA +

TNFAIP3 +

Disease Details

Synonyms
Enteropathy-Associated T-Cell Lymphoma, Type I, Enteropathy Associated T-Cell Lymphoma, Enteropathy-Type T-Cell Lymphoma, EATL, Type I
Parent(s)
Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
OncoTree Name
Enteropathy-Associated T-Cell Lymphoma
OncoTree Code
EATL

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.