NCI Definition: A low-grade malignant blood vessel neoplasm. It is characterized by the presence of epithelioid endothelial cells. The neoplastic cells are arranged in cords and nests, which are embedded in a myxoid to hyalinized stroma. 
There is 1 clinical trial for epithelioid hemangioendothelioma, of which 1 is open and 0 are completed or closed. Of the trial that contains epithelioid hemangioendothelioma as an inclusion criterion, 1 is phase 2 (1 open).
Trametinib is the most common intervention in epithelioid hemangioendothelioma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.