Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
NCI Definition: A spectrum of malignant tumors arising from the soft tissues, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms. 
There is 1 clinical trial for extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor, of which 1 is open and 0 are completed or closed. Of the trial that contains extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor as an inclusion criterion, 1 is phase 2 (1 open).
Onc201 is the most common intervention in extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.