Overview

NCI Definition: An adenocarcinoma that arises from the fallopian tube. Histologic subtypes include clear cell, endometrioid, serous, and mucinous adenocarcinoma. It spreads to adjacent organs, regional lymph nodes, and peritoneum. [1]

Fallopian tube adenocarcinomas most frequently harbor alterations in TP53, NOTCH3, CCNE1, BRD4, and SMARCA4 [2].

Most Commonly Altered Genes in Fallopian Tube Adenocarcinoma

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, TP53 Exon 8 Mutation, and TP53fs are the most common alterations in fallopian tube adenocarcinoma [2].

Top Alterations in Fallopian Tube Adenocarcinoma

Disease Details

Synonyms
Adenocarcinoma of Fallopian Tube, Adenocarcinoma of the Fallopian Tube
Parent(s)
Fallopian Tube Carcinoma
Children
Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Papillary Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, and Fallopian Tube Mucinous Adenocarcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.