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Fallopian Tube Serous Adenocarcinoma

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Associated Genetic Biomarkers

Overview

NCI Definition: A serous adenocarcinoma that arises from the fallopian tube. It is usually a high grade invasive adenocarcinoma. [1]

Fallopian tube serous adenocarcinomas most frequently harbor alterations in TP53, NOTCH3, CCNE1, BRD4, and SMARCA4 [2].

Most Commonly Altered Genes in Fallopian Tube Serous Adenocarcinoma

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, TP53 Exon 8 Mutation, and TP53fs are the most common alterations in fallopian tube serous adenocarcinoma [2].

Top Alterations in Fallopian Tube Serous Adenocarcinoma

Clinical Trials

View Clinical Trials for Fallopian Tube Serous Adenocarcinoma

Significant Genes in Fallopian Tube Serous Adenocarcinoma

BRCA1 +

BRCA2 +

Disease Details

Synonyms
Fallopian tube serous carcinoma
Parent(s)
Female Reproductive System Serous Adenocarcinoma
Children
Low Grade Fallopian Tube Serous Adenocarcinoma and High Grade Fallopian Tube Serous Adenocarcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.