Overview

NCI Definition: A neuroblastic tumor characterized by the presence of neuroblastic cells, ganglion cells, and a stroma with Schwannian differentiation constituting more than fifty-percent of the tumor volume. There are two histologic subtypes identified: ganglioneuroblastoma, intermixed and ganglioneuroblastoma, nodular. [1]

Significant Genes in Ganglioneuroblastoma

MYCN +

Disease Details

Synonyms
GANGLIONEUROBLASTOMA, MALIGNANT
Parent(s)
Neuroblastoma
Children
Ganglioneuroblastoma, Nodular, Central Nervous System Ganglioneuroblastoma, Ganglioneuroblastoma, Intermixed, and Peripheral Ganglioneuroblastoma
OncoTree Name
Ganglioneuroblastoma
OncoTree Code
GNBL

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.