Gastric Adenosquamous Carcinoma
Associated Genetic Biomarkers
NCI Definition: A carcinoma that arises from the stomach and is characterized by the presence of malignant cells with glandular and squamous differentiation. 
Gastric adenosquamous carcinomas most frequently harbor alterations in ZNF708, TP53, SMARCA4, RAD21, and PRDM1 .
ZNF708 E451D, TP53 c.217-c.1178 Missense, TP53 Mutation, TP53 Missense, and TP53 L194F are the most common alterations in gastric adenosquamous carcinoma .
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.