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Gastric Diffuse Adenocarcinoma

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Associated Genetic Biomarkers

Overview

NCI Definition: An adenocarcinoma arising from the stomach. Microscopically, it is characterized by the presence of a diffuse infiltrate, composed of individual adenocarcinoma cells or groups of adenocarcinoma cells in a fibrous or mucoid stroma. Many cells contain mucin droplets, producing a signet-ring configuration. [1]

Clinical Trials

View Clinical Trials for Gastric Diffuse Adenocarcinoma

Significant Genes in Gastric Diffuse Adenocarcinoma

CDH1 +

Disease Details

Synonyms
Adenocarcinoma of Linitis Plastica Type, Adenocarcinoma of the Linitis Plastica Type, Diffuse Adenocarcinoma of the Stomach, Diffuse Adenocarcinoma of Stomach, Diffuse Stomach Adenocarcinoma, Diffuse Gastric Adenocarcinoma
Parent(s)
Gastric Adenocarcinoma
Children
Mucinous Gastric Adenocarcinoma, Signet Ring Cell Gastric Adenocarcinoma, and Linitis Plastica
OncoTree Name
Diffuse Type Stomach Adenocarcinoma
OncoTree Code
DSTAD

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.