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Gastrointestinal Neuroendocrine Tumors

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Associated Genetic Biomarkers

Overview

NCI Definition: A well-differentiated neuroendocrine tumor arising from the digestive system. It is characterized by the presence of cells with features similar to those of the normal endocrine cells of the digestive system. The neoplastic cells express immunohistochemical evidence of neuroendocrine differentiation and hormones. There is mild to moderate nuclear atypia and less than 20 mitoses per 10 HPF. It includes well-differentiated endocrine tumors or carcinoid tumors and well-differentiated endocrine carcinomas. [1]

Clinical Trials

View Clinical Trials for Gastrointestinal Neuroendocrine Tumors

Disease Details

Synonyms
Gastrointestinal System Neuroendocrine Tumor, Digestive System Neuroendocrine Tumor, Gastroenteropancreatic NET, Gastrointestinal Neuroendocrine Tumor, Digestive System NET, Gastrointestinal NET, Gastroenteropancreatic Neuroendocrine Tumor, GEP-NET, Digestive System Well Differentiated Neuroendocrine Tumor
Parent(s)
Neuroendocrine Tumor
Children
Esophageal Neuroendocrine Tumor, Anal Canal Neuroendocrine Tumor, VIP-Producing Neuroendocrine Tumor, Colorectal Neuroendocrine Tumor, Small Intestinal Neuroendocrine Tumor, Gastrin-Producing Neuroendocrine Tumor, Somatostatin-Producing Neuroendocrine Tumor, L-Cell Glucagon-Like Peptide-Producing Neuroendocrine Tumor, Pancreatic Neuroendocrine Tumor, Appendix Neuroendocrine Tumor, and Gastric Neuroendocrine Tumor
OncoTree Name
Gastrointestinal Neuroendocrine Tumors
OncoTree Code
GINET

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.