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Grade III Meningioma

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Associated Genetic Biomarkers

Overview

Grade III meningiomas most frequently harbor alterations in NF2, CDKN2A, CDKN2B, FANCD2, and TERT [2].

Most Commonly Altered Genes in Grade III Meningioma

NF2 Mutation, NF2 Nonsense, CDKN2A Loss, NF2fs, and CDKN2B Loss are the most common alterations in grade III meningioma [2].

Top Alterations in Grade III Meningioma

Clinical Trials

View Clinical Trials for Grade III Meningioma

Disease Details

Parent(s)
Meningioma
Children
Rhabdoid Meningioma, Anaplastic Meningioma, and Papillary Meningioma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.