Overview

Grade III meningiomas most frequently harbor alterations in NF2, CDKN2A, CDKN2B, FANCD2, and TERT [2].

Most Commonly Altered Genes in Grade III Meningioma

NF2 Mutation, NF2 Nonsense, CDKN2A Loss, NF2fs, and CDKN2B Loss are the most common alterations in grade III meningioma [2].

Top Alterations in Grade III Meningioma

Disease Details

Parent(s)
Meningioma
Children
Papillary Meningioma, Anaplastic Meningioma, and Rhabdoid Meningioma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.