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Head and Neck Squamous Cell Carcinoma of Unknown Primary
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Associated Genetic Biomarkers
Overview
Head and neck squamous cell carcinoma of unknown primarys most frequently harbor alterations in TP53, CDKN2A, PIK3CA, NOTCH1, and KMT2D [2].
TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, TP53 Nonsense, and KEAP1 Mutation are the most common alterations in head and neck squamous cell carcinoma of unknown primary [2].
Significant Genes in Head and Neck Squamous Cell Carcinoma of Unknown Primary
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.