Overview

NCI Definition: A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes. [1]

Significant Genes in Hematopoietic and Lymphoid Cell Neoplasm

FGFR1 +

Disease Details

Synonyms
Hematopoietic, Including Myeloma, Malignant Hematologic Neoplasm, Hematopoietic Neoplasm, Hematologic Cancer, Hematological Tumor, Hematological Neoplasm, Hematopoietic Neoplasms including Lymphomas, Hematologic Neoplasm, Hematopoietic malignancy, NOS, Hematologic Malignancy, Hematopoietic Cancer, Malignant Hematopoietic Neoplasm, Hematopoietic Tumor, Hematopoietic Cell Tumor, Hematopoietic and Lymphoid Neoplasms
Parent(s)
Hematopoietic and Lymphoid System Neoplasm
Children
Myeloid Neoplasm, Central Nervous System Hematopoietic Neoplasm, Histiocytic and Dendritic Cell Neoplasm, Refractory Hematologic Malignancy, and Lymphocytic Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.