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High Grade Astrocytic Tumor

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Overview

High grade astrocytic tumors most frequently harbor alterations in TP53, PTEN, CDKN2A, EGFR, and CDKN2B [2].

Most Commonly Altered Genes in High Grade Astrocytic Tumor

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, CDKN2A Loss, and CDKN2B Loss are the most common alterations in high grade astrocytic tumor [2].

Top Alterations in High Grade Astrocytic Tumor

Clinical Trials

View Clinical Trials for High Grade Astrocytic Tumor

Disease Details

Parent(s)
Malignant Glioma
Children
Glioblastoma and Anaplastic Astrocytoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.