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High-Grade Endometrial Stromal Sarcoma

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Associated Genetic Biomarkers

Overview

NCI Definition: A rare, high grade sarcoma that arises from the endometrial stroma. It is characterized by round cell morphology. It was previously also known as undifferentiated uterine sarcoma. In 2014, high grade endometrial stromal sarcoma was reclassified and is currently considered a distinct and rare neoplasm. It appears to have a prognosis that falls between low grade endometrial stromal sarcoma and undifferentiated sarcoma. [1]

Clinical Trials

View Clinical Trials for High-Grade Endometrial Stromal Sarcoma

Disease Details

Synonyms
Uterine Sarcoma Favor High-Grade Endometrial Stromal Sarcoma, Uterine sarcoma, favor high-grade endometrial stromal sarcoma, YWHAE-FAM22 ESS, YWHAE-FAM22 Endometrial Stromal Sarcoma, Uterine Corpus High Grade ESS, High Grade ESS, Uterine Corpus High Grade Endometrial Stromal Sarcoma
Parent(s)
Uterine Corpus Endometrial Stromal Sarcoma
OncoTree Name
High-Grade Endometrial Stromal Sarcoma
OncoTree Code
HGESS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.