Diseases /
Indolent Non-Hodgkin Lymphoma
Back to Diseases List
Associated Genetic Biomarkers
Overview
NCI Definition: A non-Hodgkin lymphoma with an indolent clinical course. Representative examples include grade 1 and grade 2 follicular lymphoma, marginal zone lymphoma, and lymphoplasmacytic lymphoma. [1]
Indolent non-hodgkin lymphomas most frequently harbor alterations in KMT2D, TNFAIP3, ARID1A, TP53, and MYD88 [2].
KMT2D Mutation, MYD88 Mutation, MYD88 L265P, MYD88 Exon 5 Mutation, and FAT1 Mutation are the most common alterations in indolent non-hodgkin lymphoma [2].
Clinical Trials
Significant Genes in Indolent Non-Hodgkin Lymphoma
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.