Overview

NCI Definition: A benign or malignant neoplasm involving the small or large intestine. [1]

Intestinal neoplasms most frequently harbor alterations in TP53, APC, KRAS, PIK3CA, and SMAD4 [2].

Most Commonly Altered Genes in Intestinal Neoplasm

APC Mutation, TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, and KRAS Mutation are the most common alterations in intestinal neoplasm [2].

Top Alterations in Intestinal Neoplasm

Disease Details

Synonyms
Neoplasm of Intestines, Intestinal Tumors, Tumor of Intestines, Neoplasm of the Intestines, Tumor of the Intestines, Intestinal Neoplasms, Intestinal Tumor
Parent(s)
Intestinal Disorder
Children
Intestinal Benign Neoplasm, Colorectal Neoplasm, Small Intestinal Neoplasm, Colon Neoplasm, and Malignant Intestinal Neoplasm
OncoTree Name
Bowel
OncoTree Code
BOWEL

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.