Overview

NCI Definition: A central nervous system embryonal tumor, not otherwise specified arising from the brain. [1]

Significant Genes in Intracranial Primitive Neuroectodermal Neoplasm

APC +

CTNNB1 +

DDX3X +

GLI2 +

KMT2D +

MDM4 +

MYCL +

MYCN +

PPM1D +

PTCH1 +

PTEN +

SHH +

SMARCA4 +

SMO +

SUFU +

TERT +

TP53 +

YAP1 +

Disease Details

Synonyms
Intracranial Primitive Neuroectodermal Tumor, Intracranial PNET
Parent(s)
Central Nervous System Primitive Neuroectodermal Neoplasm
Children
Supratentorial Primitive Neuroectodermal Tumor

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.