Overview

NCI Definition: A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma. [1]

Kidney neoplasms most frequently harbor alterations in VHL, PBRM1, SETD2, TP53, and BAP1 [2].

Most Commonly Altered Genes in Kidney Neoplasm

VHL Mutation, PBRM1fs, SETD2 Mutation, TP53 Mutation, and PBRM1 Mutation are the most common alterations in kidney neoplasm [2].

Top Alterations in Kidney Neoplasm

Disease Details

Synonyms
Kidney Tumor, Renal Neoplasm, Neoplasm of the Kidney, Tumor of Kidney, Neoplasm of Kidney, Tumor of the Kidney, Renal Tumors, Renal Tumor
Parent(s)
Kidney and Ureter Neoplasm
Children
Kidney Neuroendocrine Neoplasm, Renal Oncocytoma, Renal Adenoma, Renal Pelvis Neoplasm, Malignant Kidney Neoplasm, Childhood Kidney Neoplasm, Kidney Angiomyolipoma, Mixed Epithelial Stromal Tumor of the Kidney, and Kidney Benign Neoplasm
OncoTree Name
Kidney
OncoTree Code
KIDNEY

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.