Kidney Small Cell Carcinoma
NCI Definition: A very rare small cell carcinoma that arises from the kidney. The prognosis is poor. 
Kidney small cell carcinomas most frequently harbor alterations in TSC2, TP53, SMC3, RB1, and PRKDC .
TSC2 Q1536*, TSC2 Mutation, TP53 c.217-c.1178 Missense, TP53 V274L, and TP53 Mutation are the most common alterations in kidney small cell carcinoma .
There is 1 clinical trial for kidney small cell carcinoma, of which 1 is open and 0 are completed or closed. Of the trial that contains kidney small cell carcinoma as an inclusion criterion, 1 is phase 1 (1 open).
Etoposide and pembrolizumab are the most common interventions in kidney small cell carcinoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.