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Kidney Wilms Tumor

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Overview

NCI Definition: An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver. [1]

Clinical Trials

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Significant Genes in Kidney Wilms Tumor

MYCN +

Disease Details

Synonyms
Wilms' tumor, Wilms Tumor of the Kidney, Wilms' Tumor of the Kidney, Renal Wilms' Tumor, Renal Wilms Tumor, Embryonal Nephroma, NEPHROBLASTOMA, MALIGNANT, Nephroblastoma
Parent(s)
Wilms Tumor
Children
Hereditary Wilms Tumor, Mixed Cell Type Kidney Wilms Tumor, Metachronous Wilms Tumor, Blastema Predominant Kidney Wilms Tumor, Epithelial Predominant Kidney Wilms Tumor, Stromal Predominant Kidney Wilms Tumor, and Nonanaplastic Kidney Wilms Tumor
OncoTree Name
Wilms' Tumor
OncoTree Code
WT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.