Large Cell Lung Carcinoma, Clear Cell Variant
Associated Genetic Biomarkers
NCI Definition: A morphologic variant of large cell lung carcinoma characterized by a predominance of clear cells that may or may not contain glycogen. 
Large cell lung carcinoma, clear cell variants most frequently harbor alterations in TP53 and STK11 .
TP53 c.217-c.1178 Missense, TP53 R283P, TP53 Mutation, TP53 Missense, and TP53 Exon 8 Mutation are the most common alterations in large cell lung carcinoma, clear cell variant .
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.