Diseases /
Liver and Intrahepatic Bile Duct Carcinoma
Overview
NCI Definition: A carcinoma that arises from the hepatocytes or intrahepatic bile ducts. The main subtypes are hepatocellular carcinoma (hepatoma) and cholangiocarcinoma. [1]
Liver and intrahepatic bile duct carcinomas most frequently harbor alterations in TP53, ARID1A, IDH1, CTNNB1, and BAP1 [2].
TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, IDH1 Mutation, and IDH1 Codon 132 Missense are the most common alterations in liver and intrahepatic bile duct carcinoma [2].
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.