NCI Definition: A localized non-invasive adenocarcinoma of the lung measuring 3 cm or less. It is characterized by a pure lepidic growth pattern and the lack of stromal, vascular, or pleural invasion. [1]

Lung adenocarcinoma in situs most frequently harbor alterations in EGFR [2].

Most Commonly Altered Genes in Lung Adenocarcinoma In Situ

EGFR Mutation are the most common alterations in lung adenocarcinoma in situ [2].

Top Alterations in Lung Adenocarcinoma In Situ

Disease Details

Stage 0 Lung Adenocarcinoma, Lung Adenocarcinoma stage 0, Bronchioloalveolar Carcinoma
Adenocarcinoma In Situ
Bronchioloalveolar Carcinoma
OncoTree Name
Lung Adenocarcinoma In Situ
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.