Overview

NCI Definition: A localized non-invasive adenocarcinoma of the lung measuring 3 cm or less. It is characterized by a pure lepidic growth pattern and the lack of stromal, vascular, or pleural invasion. [1]

Lung adenocarcinoma in situs most frequently harbor alterations in EGFR [2].

Most Commonly Altered Genes in Lung Adenocarcinoma In Situ

EGFR Mutation are the most common alterations in lung adenocarcinoma in situ [2].

Top Alterations in Lung Adenocarcinoma In Situ

Disease Details

Synonyms
Stage 0 Lung Adenocarcinoma, Lung Adenocarcinoma stage 0, Bronchioloalveolar Carcinoma
Parent(s)
Adenocarcinoma In Situ
Children
Bronchioloalveolar Carcinoma
OncoTree Name
Lung Adenocarcinoma In Situ
OncoTree Code
LAIS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.