Overview

NCI Definition: A carcinoid tumor of the lung showing focal necrotic changes or a number of mitotic figures between 2 and 10/10 high power fields. [1]

Lung atypical carcinoid tumors most frequently harbor alterations in MEN1, KMT2D, CCND1, and ATM [2].

Most Commonly Altered Genes in Lung Atypical Carcinoid Tumor

MEN1 Mutation, KMT2D Mutation, and CCND1 Amplification are the most common alterations in lung atypical carcinoid tumor [2].

Top Alterations in Lung Atypical Carcinoid Tumor

Disease Details

Synonyms
Lung atypical carcinoid, Lung Malignant Carcinoid Tumor
Parent(s)
Lung Carcinoid Tumor
OncoTree Name
Atypical Lung Carcinoid
OncoTree Code
ALUCA

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.