Overview

NCI Definition: A lymphoma composed of immature small to medium-sized precursor lymphoid cells (lymphoblasts). It includes the B- and T-cell lymphoblastic lymphoma. [1]

Significant Genes in Lymphoblastic Lymphoma

ABL1 +

AFF1 +

ALK +

ASXL1 +

BCR +

CBFB +

DEK +

DNMT3A +

ELL +

FGFR3 +

FLT3 +

IGH +

IKZF1 +

KIT +

KMT2A +

MAF +

MAFB +

MECOM +

MLF1 +

MLLT1 +

MLLT10 +

MLLT3 +

MLLT4 +

MYH11 +

NPM1 +

NUP214 +

PBX1 +

PHF6 +

RPN1 +

RUNX1 +

RUNX1T1 +

TCF3 +

TET2 +

TP53 +

WHSC1 +

Disease Details

Parent(s)
Precursor Lymphoid Neoplasm
Children
T-Cell Lymphoblastic Lymphoma and B-Cell Lymphoblastic Lymphoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.