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Malignant Cerebellar Neoplasm

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Overview

Malignant cerebellar neoplasms most frequently harbor alterations in PTCH1, KMT2D, CTNNB1, TP53, and SMO [2].

Most Commonly Altered Genes in Malignant Cerebellar Neoplasm

KMT2D Mutation, CTNNB1 Mutation, TP53 Mutation, PTCH1 Mutation, and TP53 c.217-c.1178 Missense are the most common alterations in malignant cerebellar neoplasm [2].

Top Alterations in Malignant Cerebellar Neoplasm

Clinical Trials

View Clinical Trials for Malignant Cerebellar Neoplasm

Disease Details

Parent(s)
Malignant Infratentorial Neoplasm
Children
Cerebellar Liponeurocytoma, Medulloblastoma, and Cerebellar Astrocytoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.