Overview

NCI Definition: A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma. [1]

Significant Genes in Malignant Female Reproductive System Neoplasm

ARID1A +

BRAF +

KRAS +

NF1 +

Disease Details

Synonyms
female reproductive organ cancer
Parent(s)
Malignant Reproductive System Neoplasm
Children
Malignant Ovarian Neoplasm, Female Reproductive System Serous Adenocarcinoma, Malignant Vaginal Neoplasm, Malignant Uterine Neoplasm, Malignant Placental Neoplasm, Malignant Mixed Mesodermal (Mullerian) Tumor, Female Reproductive System Papillary Adenocarcinoma, Endometrioid Adenocarcinoma, Malignant Vulvar/Vaginal Neoplasm, Malignant Fallopian Tube Neoplasm, and Endometrioid Stromal Sarcoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.