Overview

NCI Definition: A malignant neoplasm characterized by then presence of atypical giant cells. [1]

Significant Genes in Malignant Giant Cell Neoplasm

CD274 +

Disease Details

Synonyms
GIANT CELL TUMOR, MALIGNANT, Malignant Giant Cell Tumor
Parent(s)
Giant Cell Neoplasm
Children
Malignant Osteoclastic Giant Cell-Rich Tumor of Bone, Undifferentiated Pleomorphic Sarcoma with Osteoclast-Like Giant Cells, and Malignant Tenosynovial Giant Cell Tumor

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.