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Malignant Mixed Mesodermal (Mullerian) Tumor

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Overview

NCI Definition: An aggressive malignant tumor of the female reproductive system, affecting predominantly elderly menopausal women. The endometrium and ovary are the most common sites of tumor origin. Morphologically, it is a high grade tumor, composed of carcinomatous and sarcomatous elements. [1]

Clinical Trials

View Clinical Trials for Malignant Mixed Mesodermal (Mullerian) Tumor

Significant Genes in Malignant Mixed Mesodermal (Mullerian) Tumor

BRCA1 +

BRCA2 +

Disease Details

Synonyms
High-grade carcinoma c/w Mullerian primary, Poorly Differentiated Carcinoma c/w Mullerian Primary, MMMT, Malignant Mixed Mullerian Tumor, Carcinoma c/w Mullerian Primary, Carcinoma c/w M\\u00fcllerian primary
Parent(s)
Malignant Female Reproductive System Neoplasm
Children
Ovarian Carcinosarcoma, Uterine Carcinosarcoma, Fallopian Tube Carcinosarcoma, Primary Peritoneal Carcinosarcoma, and Vaginal Carcinosarcoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.