Malignant oral cavity neoplasms most frequently harbor alterations in TP53, CDKN2A, NOTCH1, PIK3CA, and KMT2D [2].

Most Commonly Altered Genes in Malignant Oral Cavity Neoplasm

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, CDKN2A Mutation, and PIK3CA Mutation are the most common alterations in malignant oral cavity neoplasm [2].

Top Alterations in Malignant Oral Cavity Neoplasm

Disease Details

Malignant Neoplasm of Mouth, Malignant Neoplasm of the Mouth, Malignant Tumor of Mouth, Malignant Oral Cavity Tumor, Malignant Mouth Tumor, Malignant Tumor of the Mouth, Malignant Mouth Neoplasm
Oral Cavity Neoplasm
Malignant Tongue Neoplasm, Malignant Buccal Mucosa Neoplasm, Malignant Floor of the Mouth Neoplasm, Oral Cavity Carcinoma, Malignant Hard Palate Neoplasm, Malignant Odontogenic Neoplasm, and Malignant Gingival Neoplasm


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.