Overview

NCI Definition: An invasive malignant neoplasm that arises from the ovary and is characterized by a predominance of clear and hobnail malignant epithelial cells. [1]

Significant Genes in Malignant Ovarian Clear Cell Tumor

ARID1A +

BRCA1 +

BRCA2 +

KDM6A +

KMT2C +

KMT2D +

SMARCA2 +

SMARCA4 +

SMARCB1 +

SS18 +

SSX1 +

SSX2 +

SSX2B +

SSX4 +

Disease Details

Synonyms
Malignant Ovarian Clear Cell Neoplasm
Parent(s)
Ovarian Clear Cell Tumor
Children
Ovarian Clear Cell Adenocarcinofibroma and Ovarian Clear Cell Adenocarcinoma
OncoTree Name
Clear Cell Ovarian Cancer
OncoTree Code
CCOV

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.