Malignant Ovarian Germ Cell Tumor
Associated Genetic Biomarkers
NCI Definition: An invasive malignant neoplasm that arises from the ovary and originates from primordial germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, dysgerminoma, and non-gestational choriocarcinoma. 
There are 7 clinical trials for malignant ovarian germ cell tumor, of which 7 are open and 0 are completed or closed. Of the trials that contain malignant ovarian germ cell tumor as an inclusion criterion, 3 are phase 1 (3 open) and 4 are phase 2 (4 open).
Aldesleukin, cyclophosphamide, and ipilimumab are the most common interventions in malignant ovarian germ cell tumor clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.