Overview

Malignant reproductive system neoplasms most frequently harbor alterations in TP53, PTEN, PIK3CA, ARID1A, and KRAS [2].

Most Commonly Altered Genes in Malignant Reproductive System Neoplasm

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, PIK3CA Mutation, and PTEN Mutation are the most common alterations in malignant reproductive system neoplasm [2].

Top Alterations in Malignant Reproductive System Neoplasm

Disease Details

Parent(s)
Reproductive System Neoplasm
Children
Sex Cord-Stromal Tumor, Uterine Ligament Cancer, Malignant Male Reproductive System Neoplasm, Rete Ovarii Adenocarcinoma, Placenta Cancer, and Malignant Female Reproductive System Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.