NCI Definition: A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain. 
There is 1 clinical trial for metastatic melanoma, of which 1 is open and 0 are completed or closed. Of the trial that contains metastatic melanoma as an inclusion criterion, 1 is early phase 1 (1 open).
Aldesleukin, cyclophosphamide, and fludarabine are the most common interventions in metastatic melanoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.