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Mucinous Breast Carcinoma

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Associated Genetic Biomarkers

Overview

NCI Definition: An invasive adenocarcinoma of the breast characterized by the presence of islands of small and uniform cells, surrounded by large amounts of mucin. Pure mucinous breast carcinomas generally have a favorable prognosis. [1]

Mucinous breast carcinomas most frequently harbor alterations in GATA3, CCND1, FGF19, BRIP1, and FGF4 [2].

Most Commonly Altered Genes in Mucinous Breast Carcinoma

GATA3fs, CCND1 Amplification, FGF19 Amplification, BRIP1 Amplification, and FGF4 Amplification are the most common alterations in mucinous breast carcinoma [2].

Top Alterations in Mucinous Breast Carcinoma

Clinical Trials

View Clinical Trials for Mucinous Breast Carcinoma

Disease Details

Synonyms
Invasive Colloid Breast Carcinoma, Colloid Breast Carcinoma, Colloid Carcinoma of Breast, Infiltrating Mucinous Breast Carcinoma, Infiltrating Colloid Breast Carcinoma, Colloid Carcinoma of the Breast, Invasive Mucinous Breast Carcinoma, Mucinous Carcinoma of the Breast, Breast Mucinous Carcinoma, Mucinous Carcinoma of Breast
Parent(s)
Mucinous Adenocarcinoma
Children
Breast Columnar Cell Mucinous Carcinoma and Breast Mucinous Cystadenocarcinoma
OncoTree Name
Breast Invasive Mixed Mucinous Carcinoma
OncoTree Code
IMMC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.