Overview

NCI Definition: An invasive adenocarcinoma of the breast characterized by the presence of islands of small and uniform cells, surrounded by large amounts of mucin. Pure mucinous breast carcinomas generally have a favorable prognosis. [1]

Mucinous breast carcinomas most frequently harbor alterations in GATA3, CCND1, FGF19, BRIP1, and FGF4 [2].

Most Commonly Altered Genes in Mucinous Breast Carcinoma

GATA3fs, CCND1 Amplification, FGF19 Amplification, BRIP1 Amplification, and FGF4 Amplification are the most common alterations in mucinous breast carcinoma [2].

Top Alterations in Mucinous Breast Carcinoma

Disease Details

Synonyms
Breast Mucinous Carcinoma, Mucinous Carcinoma of the Breast, Colloid Carcinoma of Breast, Mucinous Carcinoma of Breast, Colloid Carcinoma of the Breast, Infiltrating Colloid Breast Carcinoma, Colloid Breast Carcinoma, Infiltrating Mucinous Breast Carcinoma, Invasive Colloid Breast Carcinoma, Invasive Mucinous Breast Carcinoma
Parent(s)
Mucinous Adenocarcinoma
Children
Breast Mucinous Cystadenocarcinoma and Breast Columnar Cell Mucinous Carcinoma
OncoTree Name
Breast Invasive Mixed Mucinous Carcinoma
OncoTree Code
IMMC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.