Associated Genetic Biomarkers


NCI Definition: Multiple endocrine neoplasia caused by inactivation of the tumor suppressor gene MEN-1. Patients may develop hyperparathyroidism and parathyroid gland adenomas, pituitary gland adenomas, pancreatic islet cell neoplasms, and carcinoid tumors. [1]

Significant Genes in Multiple Endocrine Neoplasia Type 1

MEN1 +

Disease Details

Multiple Endocrine Neoplasia Type I, multiple endocrine neoplasia type 1 syndrome, MEN 1, MEN Type 1, MEA Type 1, Multiple Endocrine Adenomatosis, Type I, MEN1 syndrome, MEA Type I, Multiple Endocrine Adenomatosis Type 1, Multiple Endocrine Neoplasia, Type I, Wermer's Syndrome, Wermer Syndrome, Multiple Endocrine Adenomatosis Type I, MEN Type I
Autosomal Dominant Disorder


1. National Cancer Institute. NCI Thesaurus Version 18.11d. [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.