Overview

NCI Definition: A peripheral (mature) T-cell lymphoma presenting in the skin with patches/plaques. It is characterized by epidermal and dermal infiltration of small to medium-sized T-cells with cerebriform nuclei. Patients with limited disease generally have an excellent prognosis. In the more advanced stages, the prognosis is poor. (WHO, 2001) [1]

Significant Genes in Mycosis Fungoides

ALK +

BIRC2 +

BIRC3 +

CARD11 +

CD79A +

CD79B +

NFKBIA +

TNFAIP3 +

Disease Details

Synonyms
MF, Cutaneous T-cell lymphoma/Mycosis fungoides, CTCL/ Mycosis fungoides, mycosis fungoides
Parent(s)
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
OncoTree Name
Mycosis Fungoides
OncoTree Code
MYCF

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.