The gene ets variant 6 (ETV6) encodes for an ETS family transcription factor (Gene 2014). ETV6 is a DNA-binding protein involved in transcription regulation during embryonic development and hematopoiesis (Gene 2014; Genetics Home Reference 2014). ETV6 variants—rearrangements, in particular—have been observed in myelodysplastic syndromes, other hematologic malignancies, and sarcomas.
Suggested Citation: Strickland, S., A. Kim. 2014. ETV6. My Cancer Genome https://www.mycancergenome.org/content/disease/myelodysplastic-syndromes/etv6/?tab=0 (Updated September 23).
Last Updated: September 23, 2014