Overview

NCI Definition: A tumor mass composed of myeloblasts or immature myeloid cells. It occurs in extramedullary sites or the bone. (WHO, 2001) [1]

Significant Genes in Myeloid Sarcoma

ABL1 +

AFF1 +

BCR +

CBFA2T3 +

CBFB +

CEBPA +

CREBBP +

DEK +

ELL +

ETV6 +

FLT3 +

GLIS2 +

HOXA9 +

KAT6A +

KDM5A +

KIT +

KMT2A +

MECOM +

MLLT1 +

MLLT10 +

MLLT3 +

MLLT4 +

MNX1 +

MYH11 +

NPM1 +

NSD1 +

NUP214 +

NUP98 +

PBX1 +

PML +

RARA +

RPN1 +

RUNX1 +

RUNX1T1 +

TCF3 +

TP53 +

WT1 +

Disease Details

Synonyms
Extramedullary Myeloid Tumor, Chloroma, SARCOMA, MYELOID, MALIGNANT
Parent(s)
Myeloid Neoplasm
Children
Granulocytic Sarcoma
OncoTree Name
Myeloid Sarcoma
OncoTree Code
MS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.