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Myxofibrosarcoma

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Associated Genetic Biomarkers

Overview

NCI Definition: A malignant fibroblastic neoplasm arising from the soft tissue. It is characterized by the presence of spindle-shaped cells, cellular pleomorphism, thin-walled blood vessels, fibrous septa, and myxoid stroma. [1]

Clinical Trials

View Clinical Trials for Myxofibrosarcoma

Significant Genes in Myxofibrosarcoma

PIK3CA +

PTEN +

Disease Details

Synonyms
Myxoid Malignant Fibrous Histiocytoma, Myxoid Fibrous Histiocytoma, Myxofibrosarcoma, high-grade, Myxoid MFH, Soft tissue myxofibrosarcoma, High-grade myxofibrosarcoma
Parent(s)
Soft Tissue Fibrosarcoma
OncoTree Name
Myxofibrosarcoma
OncoTree Code
MFS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.