Overview

NCI Definition: A nonkeratinizing carcinoma which occurs predominantly in the nasopharynx but also in the tonsils and rarely in other anatomic sites. It is characterized by the presence of large malignant cells with vesicular nuclei, prominent nucleoli, syncytial growth pattern, and a lymphoplasmacytic infiltrate. [1]

Disease Details

Synonyms
Lymphoepithelial Carcinoma, Schminke Tumor, Nasopharyngeal Type Undifferentiated Carcinoma, Lymphoepithelioma-Like Carcinoma, Lymphoepithelioma
Parent(s)
Large Cell Carcinoma
Children
Oropharyngeal Undifferentiated Carcinoma, Nasopharyngeal Undifferentiated Carcinoma, and Lymphoepithelioma-Like Lung Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.