Diseases /

Neoplasm

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Overview

NCI Definition: A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. [1]

Clinical Trials

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Disease Details

Parent(s)
Disease or Disorder
Children
Neoplasm by Site, Eye Neoplasm, Neoplasm by Special Category, Cancer, Hematopoietic and Lymphoid System Neoplasm, Solid Neoplasm, Neoplasm by Morphology, Reproductive System Neoplasm, Papillary Neoplasm, Benign Neoplasm, and Skin Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.