NCI Definition: A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. 
Neoplasms most frequently harbor alterations in TP53, KRAS, PIK3CA, APC, and CDKN2A .
TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, KRAS Mutation, and KRAS Exon 2 Mutation are the most common alterations in neoplasm .
There is 1 clinical trial for neoplasm, of which 1 is open and 0 are completed or closed. Of the trial that contains neoplasm as an inclusion criterion, 1 is phase 1 (1 open).
Bevacizumab, cetuximab, and temsirolimus are the most common interventions in neoplasm clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.