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NUT Midline Carcinoma of the Head and Neck

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Associated Genetic Biomarkers

Overview

NUT midline carcinoma of the head and necks most frequently harbor alterations in NUTM1, EP300, BRD4, TMPRSS2, and RFWD2 [2].

Most Commonly Altered Genes in NUT Midline Carcinoma of the Head and Neck

NUTM1 Fusion, NUTM1-BRD4 Fusion, BRD4-NUTM1 Fusion, BRD4 Fusion, and TMPRSS2-KLF4 Fusion are the most common alterations in NUT midline carcinoma of the head and neck [2].

Top Alterations in NUT Midline Carcinoma of the Head and Neck

Clinical Trials

View Clinical Trials for NUT Midline Carcinoma of the Head and Neck

Significant Genes in NUT Midline Carcinoma of the Head and Neck

MYCN +

NUTM1 +

Disease Details

Parent(s)
NUT Carcinoma
OncoTree Name
NUT Midline Carcinoma of the Head and Neck
OncoTree Code
NMCHN

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.