Overview

Oral neoplasms most frequently harbor alterations in TP53, CDKN2A, NOTCH1, PIK3CA, and KMT2D [2].

Most Commonly Altered Genes in Oral Neoplasm

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, CDKN2A Mutation, and PIK3CA Mutation are the most common alterations in oral neoplasm [2].

Top Alterations in Oral Neoplasm

Disease Details

Parent(s)
Head and Neck Neoplasm
Children
Malignant Oral Neoplasm, Oral Intraepithelial Neoplasia, and Oral Cavity Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.