Oral neoplasms most frequently harbor alterations in TP53, CDKN2A, NOTCH1, PIK3CA, and KMT2D [2].

Most Commonly Altered Genes in Oral Neoplasm

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, CDKN2A Mutation, and PIK3CA Mutation are the most common alterations in oral neoplasm [2].

Top Alterations in Oral Neoplasm

Disease Details

Head and Neck Neoplasm
Malignant Oral Neoplasm, Oral Intraepithelial Neoplasia, and Oral Cavity Neoplasm


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.