Overview

NCI Definition: An embryonal carcinoma arising from the ovary. Signs and symptoms include the presence of an abdominal mass and abdominal pain. [1]

Ovarian embryonal carcinomas most frequently harbor alterations in CDKN1B, ETV6, CCND2, RAD52, and KRAS [2].

Most Commonly Altered Genes in Ovarian Embryonal Carcinoma

CDKN1B Amplification, CCND2 Amplification, ETV6 Amplification, RAD52 Amplification, and KRAS Amplification are the most common alterations in ovarian embryonal carcinoma [2].

Top Alterations in Ovarian Embryonal Carcinoma

Disease Details

Synonyms
Embryonal Carcinoma of Ovary, Embryonal Carcinoma of the Ovary
Parent(s)
Embryonal Carcinoma
Children
Childhood Ovarian Embryonal Carcinoma
OncoTree Name
Embryonal Carcinoma
OncoTree Code
OEC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.