Overview

NCI Definition: A benign, borderline, or malignant tumor that originates from the surface epithelium of the ovary. It is composed of epithelial cells and stroma. Representative examples of benign tumors include serous cystadenoma, mucinous cystadenoma, and benign Brenner tumor. Representative examples of borderline tumors include serous surface papillary tumor, mucinous adenofibroma, and borderline Brenner tumor. Representative examples of malignant tumors include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, and malignant Brenner tumor. [1]

Significant Genes in Ovarian Epithelial Tumor

CDK4 +

CDK6 +

EGFR +

Disease Details

Synonyms
Epithelial Neoplasm of Ovary, Ovarian Surface Epithelial-Stromal Tumor, Epithelial Tumor of the Ovary, Epithelial Neoplasm of the Ovary, Epithelial Tumor of Ovary, Ovarian Surface-Epithelial Stromal Neoplasm
Parent(s)
Ovarian Neoplasm
Children
Ovarian Squamous Cell Tumor, Ovarian Brenner Tumor, Ovarian Mixed Epithelial Tumor, Borderline Ovarian Epithelial Tumor, Malignant Ovarian Epithelial Tumor, Ovarian Endometrioid Tumor, Ovarian Transitional Cell Tumor, Ovarian Papillary Tumor, Ovarian Serous Tumor, Ovarian Clear Cell Tumor, and Ovarian Mucinous Tumor
OncoTree Name
Ovarian Epithelial Tumor
OncoTree Code
OVT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.