Ovarian Germ Cell Tumor
NCI Definition: A neoplasm that arises from the ovary and originates from germ cells. Representative examples include teratoma, embryonal carcinoma, yolk sac tumor, and dysgerminoma. 
Ovarian germ cell tumors most frequently harbor alterations in TP53, KRAS, KMT2D, PIK3CD, and PIK3CA .
TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, TP53 Exon 5 Mutation, and KMT2D Mutation are the most common alterations in ovarian germ cell tumor .
There is 1 clinical trial for ovarian germ cell tumor, of which 1 is open and 0 are completed or closed. Of the trial that contains ovarian germ cell tumor as an inclusion criterion, 1 is phase 2 (1 open).
Nilotinib and paclitaxel are the most common interventions in ovarian germ cell tumor clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.