Overview

NCI Definition: A benign, borderline, or malignant epithelial tumor of the ovary characterized by the presence of neoplastic epithelial cells that contain intracytoplasmic mucin and may resemble the epithelial cells of the endocervix or gastrointestinal tract. [1]

Ovarian mucinous tumors most frequently harbor alterations in KRAS [2].

Most Commonly Altered Genes in Ovarian Mucinous Tumor

KRAS Mutation, KRAS Exon 2 Mutation, and KRAS Codon 12 Missense are the most common alterations in ovarian mucinous tumor [2].

Top Alterations in Ovarian Mucinous Tumor

Disease Details

Synonyms
Mucinous Tumor of the Ovary, Mucinous Neoplasm of the Ovary, Mucinous Tumor of Ovary, Ovarian Mucinous Neoplasm, Mucinous Neoplasm of Ovary
Parent(s)
Ovarian Epithelial Tumor
Children
Borderline Ovarian Mucinous Tumor

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.